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Disease Reportshot flashes
MeSH D019584 - hot flashes
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Competitive Landscape
Events Timeline
Commercial
Clinical Trials
Competitive landscape
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D012816:Signs and symptoms
0 Companies
0 Drugs
Success rate
D019584: 
Hot flashes
86 Companies
27 Drugs
$
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
AbbVieEstradiol Alora  1996-12-20   
Estradiol, Elagolix Oriahnn 2024-09-10 2020-05-29 $145 M Y2021 
Agile TherapeuticsEthinyl estradiol, Levonorgestrel Twirla 2028-07-10 2020-02-14   
Ajanta PharmaClonidine Clonidine  2017-11-20   
Alembic PharmaceuticalsClonidine Clonidine  2011-12-06   
AllerganEthinyl estradiol, Norethindrone Brevicon  1982-01-01   
Estradiol Estrace  1984-01-31   
Ethinyl estradiol, Norethindrone Estrostep Fe  1996-10-09   
Ethinyl estradiol, Norethindrone Femcon Fe  2003-11-14   
Ethinyl estradiol, Norethindrone Femhrt  1999-10-15   
Estradiol Femtrace 2025-10-02 2004-08-20   
Ethinyl estradiol, Norethindrone Lo Loestrin Fe 2029-02-02 2010-10-21   
Ethinyl estradiol, Norethindrone Lo Minastrin Fe 2029-02-02 2013-07-24   
Ethinyl estradiol, Norethindrone Minastrin  2013-05-08   
Ethinyl estradiol, Norethindrone Norinyl 1+35  1982-01-01   
Ethinyl estradiol, Norethindrone Taytulla  2013-04-19   
Clonidine Clonidine  1987-03-23   
Ethinyl estradiol, Desogestrel Desogestrel Ethinyl Estradiol  2005-07-29   
Ethinyl estradiol, Drospirenone Drospirenone Ethinyl Estradiol  2011-11-28   
Ethinyl estradiol, Drospirenone, Levomefolate Drospirenone, Ethinyl Estradiol Levomefolate  2016-10-11   
Estradiol Estradiol  1982-01-01   
Estrone Estrone  1982-01-01   
Estropipate Estropipate  1993-09-23   
Ethinyl estradiol, Levonorgestrel Levonorgestrel Ethinyl Estradiol  2011-06-06   
Ethinyl estradiol, Levonorgestrel Levora  1993-12-13   
Estrone Natural Estrogenic Substance-estrone  1982-11-23   
Ethinyl estradiol, Norethindrone Norethin  1988-04-12   
Ethinyl estradiol, Norethindrone Norethindrone Ethinyl Estradiol  1987-01-29   
Ethinyl estradiol, Norethindrone Norethindrone Ethinyl Estradiol ()  1991-09-24   
Ethinyl estradiol, Norgestimate Norgestimate Ethinyl Estradiol  2006-08-17   
Ethinyl estradiol, Norgestrel Ogestrel  1999-12-15   
Ethinyl estradiol, Levonorgestrel Quasense  2006-09-06   
Estradiol, Testosterone undecanoate Testosterone Cypionate-estradiol Cypionate  1986-03-13   
Estradiol, Testosterone enanthate Testosterone Enanthate Estradiol  1982-01-01   
Ethinyl estradiol, ETHYNODIOL Zovia  1991-12-30   
AlvogenEstradiol Estradiol  2018-03-05   
American RegentClonidine Clonidine  2009-10-08   
Estradiol Estradiol  2010-01-19   
American TherapeuticsClonidine Clonidine  1986-07-08   
Amneal PharmaceuticalsEstradiol, Norethindrone Activella  1998-11-18   
Clonidine Clonidine  2017-11-20   
Ethinyl estradiol, Etonogestrel Eluryng  2019-12-11   
Estradiol Estradiol  2015-05-29 $113.587 M Q3/18-Q2/19 
Estradiol, Progesterone Estradiol Progesterone  2022-05-16   
Ethinyl estradiol, Norelgestromin Ethinyl Estradiol Norelgestromin  2021-02-25   
Ethinyl estradiol, Levonorgestrel Levonorgestrel Ethinyl Estradiol  2014-12-08   
Ethinyl estradiol, Norethindrone Norethindrone Ethinyl Estradiol Ferrous  2009-09-01   
Ethinyl estradiol, Norgestimate Norgestimate Ethinyl Estradiol  2015-10-27   
ApotexEthinyl estradiol, Drospirenone Drospirenone Ethinyl Estradiol  2016-09-21   
Ethinyl estradiol, Norethindrone Norethindrone Ethinyl Estradiol Ferrous  2018-03-21   
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Clinical Trials
Historical Success Rate
Phase 1
36%
4/11
Phase 2
54%
13/24
Phase 3
33%
12/36
Approved: 7Overall Success rate: 7%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
AbbVie
Estradiol,
Estradiol benzoate,
Estradiol valerate
Agile Therapeutics
Ethinyl estradiol,
Levonorgestrel
Allergan
Estradiol,
Estradiol benzoate,
Estradiol valerate,
Estrone,
Ethinyl estradiol,
Levonorgestrel,
Norethindrone,
Norgestimate,
Norgestrel,
Testosterone enanthate,
Testosterone undecanoate
Alvogen
Estradiol,
Estradiol benzoate,
Estradiol valerate
Amneal Pharmaceuticals
Estradiol,
Estradiol benzoate,
Estradiol valerate,
Levonorgestrel
Ascend Therapeutics
Estradiol,
Estradiol benzoate,
Estradiol valerate
Astellas Pharma
Fezolinetant,
Escitalopram,
Endocrine,
Catapresan,
Ccb,
Lexapro,
Ssri
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